Printer Friendly Version

Definitions Current Terminology

WHAT IS CELIAC DISEASE?

A multidiscliplinary task force of 16 physicians from seven countries reviewed and evaluated current terminology during a meeting in Oslo, Norway. These definitions are the results.

Coeliac / Celiac disease (CD) ‒ A chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals.

Terms not currently recommended: SPRUE, COELIAC SPRUE, GLUTEN-SENSITIVE ENTEROPATHY AND GLUTEN INTOLERANCE, NON-TROPICAL SPRUE AND IDIOPATHIC STEATORRHOEA

Asymptomatic CD ‒ Asymptomatic CD is not accompanied by symptoms commonly associated with CD and have no symptoms that respond to gluten withdrawal, even in response to direct questioning.

Term not currently recommended: SILENT CD

Subclinical CD ‒ Unsuspected CD when the threshold of clinical detection without signs or symptoms sufficient to trigger CD testing in routine practice.

Terms not currently recommended: NON-CLASSICAL CD, LATENT CD

Symptomatic CD ‒ Characterized by clinically evident gastrointestinal and/or extra intestinal symptoms attributable to gluten intake.

Terms not currently recommended: CLASSICAL CD, TYPICAL CD, ATYPICAL CD, OVERT CD

Potential CD ‒ Normal small intestinal mucosa in person at increased risk of developing CD as indicated by positive CD serology. Non-celiac gluten sensitivity (NCGS) ‒ Relates to one or more of a variety of immunological, morphological or symptomatic manifestations that are precipitated by the ingestion of gluten in people in whom CD has been excluded.

Term not currently recommended: GLUTEN SENSITIVITY

Gluten-related disorders ‒ Recommended term to describe all conditions related to gluten. This may include disorders such as gluten ataxia, dermatitis herpetiformis, non-celiac gluten sensitivity (NCGS) and CD.

Term not currently recommended: GLUTEN INTOLERANCE

Reference

The Oslo definitions for coeliac disease and related terms, Jonas F. Ludvigsson, Daniel A. Leffler, Julio C. Bai, et al, Gut published online February 16, 2012, doi: 10.1136/gutin 1-2011-301346

Reviewed 2/19/2013