Vocabulary Evolution of Celiac Disease

A multidiscliplinary task force of 16 physicians from seven countries reviewed and evaluated current terminology during a meeting in Oslo, Norway. These definitions are the results.

Coeliac / Celiac disease (CD)

A chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals.
Terms not currently recommended: SPRUE, COELIAC SPRUE, GLUTENSENSITIVE ENTEROPATHY AND GLUTEN INTOLERANCE, NON-TROPICAL SPRUE AND IDIOPATHIC STEATORRHOEA

Asymptomatic CD

Asymptomatic CD is not accompanied by symptoms commonly associated with CD and have no symptoms that respond to gluten withdrawal, even in response to direct questioning.
Term not currently recommended: SILENT CD

Potential CD

Normal small intestinal mucosa in person at increased risk of developing CD as indicated by positive CD serology.

Subclinical CD

Unsuspected CD when the threshold of clinical detection without signs or symptoms sufficient to trigger CD testing in routine practice. Terms not currently recommended: NON-CLASSICAL CD, LATENT CD

Symptomatic CD

Characterized by clinically evident gastrointestinal and/or extra intestinal symptoms attributable to gluten intake.
Terms not currently recommended: CLASSICAL CD, TYPICAL CD, ATYPICAL CD, OVERT CD

Non-coeliac gluten sensitivity (NCGS)

Relates to one or more of a variety of immunological, morphological or symptomatic manifestations that are precipitated by the ingestion of gluten in people in whom CD has been excluded.
Term not currently recommended: GLUTEN SENSITIVITY

Gluten-related disorders

Recommended term to describe all conditions related to gluten. This may include disorders such as gluten ataxia, dermatitis herpetiformis, non-coeliac gluten sensitivity (NCGS) and CD.
Term not currently recommended: GLUTEN INTOLERANCE

 

REFERENCE: The Oslo definitions for coeliac disease and related terms, Jonas F. Ludvigsson, Daniel A. Leffler, Julio C. Bai, et al, Gut published online February 16, 2012, doi:10.1136/gutin 1-2011-301346